| 1. | | My 16-month theanine self-experiment (dynomight.net) |
| 817 points by dynm on March 9, 2025 | 435 comments |
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| 2. | | 670nm red light exposure improved aged mitochondrial function, colour vision (nature.com) |
| 333 points by walterbell on Feb 16, 2025 | 223 comments |
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| 3. | | We fine-tuned Llama 405B on AMD GPUs (publish.obsidian.md) |
| 495 points by felarof on Sept 23, 2024 | 101 comments |
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| 4. | | Antibiotics damage the colonic mucus barrier in a microbiota-independent manner (science.org) |
| 83 points by cpncrunch on Sept 12, 2024 | 63 comments |
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| 5. | | Creating a Git Commit: The Hard Way (avestura.dev) |
| 288 points by avestura on Sept 4, 2024 | 38 comments |
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| 6. | | OAuth from First Principles (stack-auth.com) |
| 490 points by n2d4 on Sept 1, 2024 | 104 comments |
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| 7. | | The introverts are winning (newhumanist.org.uk) |
| 169 points by johntfella on Aug 4, 2024 | 181 comments |
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| 8. | | It's getting harder to die (plough.com) |
| 242 points by baud147258 on June 25, 2024 | 249 comments |
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| 9. | | The ketogenic diet improves healthspan and memory in aging mice (medicalxpress.com) |
| 47 points by PaulHoule on June 27, 2024 | 34 comments |
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| 10. | | AI Revolutionized Protein Science, but Didn't End It (quantamagazine.org) |
| 107 points by sblank on June 27, 2024 | 36 comments |
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| 11. | | Wc2: Investigates optimizing 'wc', the Unix word count program (github.com/robertdavidgraham) |
| 253 points by PaulHoule on June 20, 2024 | 150 comments |
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| 12. | | An air quality model that is evolving with the times (eos.org) |
| 144 points by Brajeshwar on May 28, 2024 | 44 comments |
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| 13. | | Show HN: Peanut Butter Spinner (cdaringe.com) |
| 193 points by cdaringe on May 18, 2024 | 145 comments |
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| 14. | | A review on protein language models (apoorva-srinivasan.com) |
| 138 points by apoorva26 on May 14, 2024 | 27 comments |
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| 15. | | It's always TCP_NODELAY (brooker.co.za) |
| 884 points by todsacerdoti on May 9, 2024 | 268 comments |
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| 16. | | Deaf girl is cured in world first gene therapy trial (independent.co.uk) |
| 704 points by belter on May 9, 2024 | 335 comments |
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| 17. | | AlphaFold 3 predicts the structure and interactions of life's molecules (blog.google) |
| 1100 points by zerojames on May 8, 2024 | 487 comments |
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| 18. | | Decline in heart failure deaths has been undone, led by people under 45 (statnews.com) |
| 36 points by gulced on April 24, 2024 | 32 comments |
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| 19. | | I should have loved biology (2020) (jsomers.net) |
| 685 points by paulgb on April 21, 2024 | 253 comments |
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| 20. | | Embeddings are a good starting point for the AI curious app developer (bawolf.substack.com) |
| 675 points by bryantwolf on April 17, 2024 | 174 comments |
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| 21. | | An FDA approved device offers a new treatment for tinnitus (npr.org) |
| 303 points by andsoitis on April 15, 2024 | 178 comments |
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| 22. | | M 4.8 – 2024 Whitehouse Station, New Jersey Earthquake (usgs.gov) |
| 453 points by theandrewbailey on April 5, 2024 | 355 comments |
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| 23. | | Metal thought to be International Space Station trash rips through Florida home (theguardian.com) |
| 22 points by giuliomagnifico on April 2, 2024 | 5 comments |
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| 24. | | More powerful Go execution traces (go.dev) |
| 376 points by nalgeon on March 14, 2024 | 148 comments |
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| 25. | | Debugging a Golang Bug with Non-Blocking Reads (scratchdata.com) |
| 52 points by memset on March 11, 2024 | 6 comments |
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| 26. | | Sugar: An activity-focused, open-source software learning platform for children (sugarlabs.org) |
| 182 points by bane on March 6, 2024 | 83 comments |
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| 27. | | The Era of 1-bit LLMs: ternary parameters for cost-effective computing (arxiv.org) |
| 1040 points by fgfm on Feb 28, 2024 | 447 comments |
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| 28. | | All you need is Wide Events, not "Metrics, Logs and Traces" (isburmistrov.substack.com) |
| 267 points by talboren on Feb 27, 2024 | 175 comments |
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| 29. | | Cactus – A Modern Diablo II Version Switcher, Character Isolator, & Mod Manager (github.com/fearedbliss) |
| 108 points by fearedbliss on Feb 26, 2024 | 72 comments |
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| 30. | | Our Company Is Doing So Well That You're All Fired (mcsweeneys.net) |
| 409 points by ohjeez on Feb 22, 2024 | 317 comments |
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