Tcl/Tk to this day is the best tool to make GUI frontends for CLI applications. Besides that, in the past I used it in production for intranet database entry applications. It has since been replaced by Flask. In my opinion the higher complexity of the Flask version is no way justified and we should have kept the much simpler ~2k LOC Tcl/Tk solution.
CLI applications typically read text from stdin and write text to stdout. The tcl model of "everything is a string" makes exactly the right abstraction to create GUI frontends for CLI applications rapidly and keep them simple at the same time.
Tk's GUI object model is sitting at a reasonable maxima between trivial to make use of vs. triggering the events necessary to make the GUI active.
Small example. You want a button on your GUI that triggers a procedure called "process" when it is clicked, this is the code you need (if you are fine with the remaining defaults) (and assuming you used 'pack' as the geometry manager):
button .process -text "Process Entries" -command process
pack .process -side top
And a fully active GUI button will now appear at the bottom of your Tk window, with a label of "Process Entries" and when you click it, a Tcl procedure named "process" will be executed.
For jimtcl (the production-ready minimalistic tcl implementation which antires started (with full closures & gc'able lambdas) - probably an outgrowth of picol), you can get static "(some) batteries included" binaries at: